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4.1 Nitrates. Consistent with its known effects on the nitric oxide/cGMP pathway [see Clinical Pharmacology (12.1, 12.2)], VIAGRA was shown to potentiate the hypotensive effects of nitrates, and its administration to patients who are using nitric oxide donors such as organic nitrates or organic nitrites in any form either regularly and/or intermittently is therefore contraindicated. When taking Viagra for the first time, there s a few ways you can prepare: Eat a light meal – Although Viagra can be taken with and without food, a large or full fat meal can delay absorption; Give yourself time – You won t instantly get an erection when taking Viagra, it can take minutes to begin to feel the effect. buy viagra 60 pills Viagra and certain drugs for pulmonary arterial hypertension (PAH). The manufacturer of Viagra advises that certain drugs for PAH should not be taken with Viagra. Due to this interaction, doctors typically will not prescribe Viagra with these drugs. Examples include: riociguat (Adempas) sildenafil (Revatio) tadalafil (Adcirca) Viagra (sildenafil) is a prescription drug that s used to treat erectile dysfunction (ED). The drug comes as an oral tablet. It s usually taken as needed about 1 hour before sexual activity.